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D i p o n E D C R S
  • Call Us: +91 7892174835
  • E-mail : info@diponedcrs.com
  • Corporate:121F, Bommasandra Industrial Area, 1 st Phase, Hulimangala Road, Hosur Main Road, Bengaluru 560099, India

Drug Discovery

Toxicology Studies

General Toxicology

  • Acute oral toxicity
  • Acute dermal toxicity
  • Acute dermal irritation/Corrosion
  • Acute eye irritation/corrosion
  • Acute systemic
  • Skin sensitization
  • Repeated dose 14,21/28, 90, 180 & 365 Days - (oral, dermal, parenteral)
  • Combined chronic and reproduction/ developmental toxicity screening
  • One/Multi Generation Reproduction toxicity
  • Prenatal developmental toxicity study

Genetic Toxicology

  • AMES (Bacterial Reverse Mutation Assay) - Salmonella typhimurium (TA 98, TA100, TA102, TA1535, TA1537) Strains.
  • In Vitro chromosomal aberration using human lymphocytes (Structural and numerical aberrations) - Primary cell cultures of human blood lymphocytes (V79 cell lines).
  • In Vivo Micronucleus Toxicity Study - Mice.
  • In Vitro Mammalian Cell Micronucleus Test - (chromosomal breaks and aneuploidy resulting in micronuclei formation) - Clastogenic -V79 cell lines.
  • In Vitro Cytotoxicity Assay - L929 and HEK 293 cells.

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